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Fat-dissolving injection ingredients: What is left out is what matters.

June 22, 2026shioclinic
Fat-dissolving injection ingredients: What is left out is what matters.

Hello, this is Sio Clinic.

We have been receiving many inquiries about fat-dissolving injections lately.

As a clinic that researches and performs these procedures in detail,

we believe that beyond effectiveness, it is crucial to exclude unnecessary ingredients.

We believe that a fat-dissolving injection

should be designed to be clean rather than aggressive.

Many people asking about our 'Clean Cut' procedure often inquire about

the dosage (cc) or how quickly it works.

While dosage is important,

it is even more critical to check which ingredients are included and which ones are excluded.

We believe a fat-dissolving injection should not just be about making the face look slimmer for a moment.

We created 'Clean Cut' because we believe that procedures designed to create clean lines should also use clean ingredients.

<Clean Cut with clean ingredients>

The core ingredients that directly reduce fat are categorized into DCA and CA.

Among them, the original products approved in Korea include V-OLET and New Bijou.

This led us to think.

We carefully considered which ingredients should not be in Clean Cut.

1. Steroids: They can help reduce inflammation and swelling.

When included in fat-dissolving injections and acting on the skin or subcutaneous fat layer, they can cause localized skin atrophy, fat atrophy, and pigment changes. Excessive steroid use can lead to hair loss, thinning skin, and potential skin depression. Furthermore, it can cause menstrual cycle changes or irregular bleeding. Therefore, we have boldly removed steroids from Clean Cut.

2. Hyaluronidase: An enzyme that breaks down hyaluronic acid.

It is used to dissolve fillers. When hyaluronidase enters our body, it can cause allergic reactions.

Also, hyaluronic acid naturally exists in our skin and subcutaneous tissues. Because hyaluronidase can dissolve components in the extracellular matrix, it may reduce the skin's moisture, elasticity, and structural support.

3. PPC: A commonly used ingredient in the past. It was used alongside DCA rather than directly destroying fat on its own.

However, issues such as inflammatory reactions, pain, swelling, nodules, skin irregularities, and tissue damage have been reported with PPC. Reactions like inflammation, necrosis, and fibrosis have also been observed. Moreover, because it has a high potential to leave behind lumps and uneven tissue, we consider PPC an unclean ingredient.

4. Diuretics: They may appear to reduce swelling by draining water.

However, we believe the purpose of a fat-dissolving injection is to refine the fat layer, not to remove water. Additionally, diuretics can cause dehydration, electrolyte imbalance, dizziness, and hypotension, and in severe cases, even pose a risk of arrhythmia.

That is why we created Clean Cut, which contains none of these four ingredients.

We have explained why Sio Clinic's Clean Cut, a fat-dissolving injection for those who want to look beautiful while being mindful of ingredients, does not contain these four substances.

In the link below, we have also written about why we use ultrasound during Clean Cut procedures, so please check that out as well!

This article is adapted from SHIO Clinic's official Naver blog.

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